주요 연구 분야
Research Area
Site-specific Protein Modification
-"Marking-Activation-Coupling" approach to attach various functional handles to protein
-Site-specific, authentic protein modification
Genetic Incorporation of
Unnatural Amino Acids into Proteins
- Development of new method for incorporation of unnatural amino acid into proteins
- Design and engineering of new translation machinery for genetic code expansion
Phosphoserine Incorporation
Application of synthetic biology techniques to basic cell biology and applied medical science
- Detailed mapping of protein kinase signaling network
- Anti-cancer drug design based on activated target protein-ligand structure/modeling
- High-throughput screening of kinase inhibitors for cancer therapy
Protein Engineering and Directed Evolution
- Development of new strategy for the redesign of proteins with novel function
- Rational design of proteins based on structure analysis
- Molecular evolution of proteins for enhanced properties